KISUNLA® Infusion Therapy

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About KISUNLA® Infusion Therapy

KISUNLA® is approved by the FDA for treating early Alzheimer's disease. It works by targeting and removing amyloid beta plaques in the brain, which are protein clumps that contribute to memory and thinking problems in Alzheimer's disease.

Condition treated by this therapy

KISUNLA® is used to treat early symptomatic Alzheimer's disease, which incluides people with mild cognitive impairement (MCI) as well as people in the mild dementia stagr of Alzheimer's disease who have confirmed amyloid pathology.

This medication is specifically for people in the earlier stages of Alzheimer's who have been confirmed to have amyloid protein buildup in their brain through testing.

KISUNLA® Price

The out-of-pocket KISUNLA® price will vary depending on your insurance coverage. If you have questions about your coverage, contact your insurance provider.

No patient should go without necessary treatment due to financial limitations. If you have questions about financial assistance opportunities, contact a member of our Violet Health team.

What to Expect During KISUNLA® Infusion Therapy

KISUNLA® is given through an intravenous infusion. Each infusion typically takes about 30 minutes to complete.

Before starting treatment, your doctor will:

Perform MRI brain scans to establish a baseline
Likely test for a specific genetic factor (APOE-E4) that could increase your risk of side effects
Ask about all medications you are taking, especially blood thinners

During your treatment course you'll have regular MRI scans to monitor for any changes in your brain. Unlike other Alzheimer's medications, you may be able to stop taking KISUNLA® once PET scans show your amyloid levels have decreased sufficiently. In clinical trials, about 17% of patients were able to stop after 6 months, 47% after a year, and 69% after 18 months.

KISUNLA® Side Effects

The most significant concern is a condition called ARIA (Amyloid-Related Imaging Abnormalities). ARIA appears as temporary swelling or small spots of bleedingin areas of your brain. While many people don't experience symptoms of ARIA, it can be potnetially serious. Symptoms include:

Temporary swelling in areas of the brain
Spots of bleeding on the surface of or in the brain
In rare cases, larger areas of bleeding in the brain
Headache (most common general side effect)
Nausea
Dizziness
Confusion
Changes in vision
Difficulty walking
Seizures (rare)

Possible Infusion-related reactions include:

Sweating
Skin irritation
Headache
Nausea
Chest pain
Vomiting
Breathing problems
Chills
Fever
Swelling of the face

Hightened risk factors for side effects include having a specific genetic risk factor (homozygous apolipoprotein E ε4 gene carriers) and taking blood thinning medications. Remember to immediately report any side effects to your healthcare provider, especially if you experience symptoms that could indicate ARIA, which my require immediate medical attention.

KISUNLA® Infusion Therapy at Violet Health

Your comfort during KISUNLA® infusion therapy at Violet Health is our priority. Our KISUNLA®patients enjoy walk-up parking, complimentary entertainment and snacks, and a team of highly trained providers during each treatment. Plus, Violet Health’s evening and weekend hours and convenient city and rural locations make it easier to schedule your appointments.

Violet Health Infusion Centers provides infusion therapy for patients with rare, chronic, or complex conditions in a comfortable, patient-centered atmosphere.

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Helpful Resources

Patient Forms

Before you attend your first appointment at Violet Health, please make sure to review the documents below. Please contact us if you have any questions!