BRIUMVI® Infusion Therapy

BRIUMVI® (ublituximab-xiiy) is a treatment for adults with relapsing multiple sclerosis that targets specific immune cells involved in MS, requiring only a one-hour infusion twice yearly after initial treatment, making it both effective at reducing relapses and convenient for your lifestyle.

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About BRIUMVI® Infusion Therapy

BRIUMVI® (ublituximab-xiiy) is a CD20-directed monoclonal antibody that works to slow disease progression in relapsing multiple sclerosis by depleting immune B-cells. It targets a unique epitope on CD20-expressing B-cells, which has proven to be an important therapeutic approach for managing autoimmune disorders like relapsing multiple sclerosis (RMS). It is the only B-cell therapy for RMS that can be administered in a one-hour infusion, twice per year, following the initial starting doses.

Conditions treated by this therapy

BRIUMVI® is approved to treat adult patients with relapsing forms of multiple sclerosis (MS), which include:

Clinically isolated syndrome
Relapsing-remitting disease
Active secondary progressive disease

BRIUMVI® Price

The cost of BRIUMVI® can vary depending on your insurance coverage. If you're concerned about the price of your medication:

Contact your insurance provider to understand your coverage
Ask your doctor or pharmacist about lower-cost alternatives
Check with the drug manufacturer about financial assistance programs
Explore patient assistance options if you're uninsured or underinsured

Remember, many resources exist to help patients access necessary medications. Don't hesitate to ask for help if you're struggling with medication costs. No patient should go without necessary treatment due to financial limitations. If you have questions about financial assistance opportunities, contact a member of our Violet Health team.

What to Expect During BRIUMVI® Infusion Therapy

When receiving BRIUMVI®, you'll start with a 4-hour infusion followed by a 1-hour infusion two weeks later. Then continue with just two 1-hour infusions per year. Before your infusion, it is important to drink plenty of water and come to your appointment hydrated.

Your dedicated Infusion nurse will check your vitals and review your medical history to check for improvements or potential side effects of your infusion therapy.
Your nurse will begin your infusion and check in on you periodically during your treatment.
After your infusion, your nurse will monitor you to ensure you do not have any complications or reactions to the infusion therapy.

BRIUMVI® Side Effects

More common side effects of BRIUMVI®

Upper respiratory tract infections
Infusion reactions ranging from mild to severe
- Reqaction that may occure during infusion include fever, chills, headache, influenza-like illness, elevated heart rate, nausea, throat irritation, and skin redness

Always consult with your healthcare provider for complete information about potential side effects and to discuss any concerns you may have about treatment.

BRIUMVI® Infusion Therapy at Violet Health

Your comfort during BRIUMVI® infusion therapy at Violet Health is our priority. Our patients enjoy walk-up parking, complimentary entertainment and snacks, and a team of highly trained providers during each treatment. Plus, Violet Health’s evening and weekend hours and convenient city and rural locations make it easier to schedule your appointments.

Violet Health Infusion Centers provides infusion therapy for patients with rare, chronic, or complex conditions in a comfortable, patient-centered atmosphere.

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Before you attend your first appointment at Violet Health, please make sure to review the documents below. Please contact us if you have any questions!